Reigns was struck by the horrible disease for the second time 11 years after putting it in remission last October and suddenly relinquished the Universal Championship in order to start treatment.
The Big Dog was feeling quite intimidated about disclosing such sensitive information to the crowd, which tended to boo him at the time even though he wrestled as a babyface because they didn’t agree with the way he was being booked as the company’s top star.
However, the ex-WWE Champion went ahead with the plan and quickly realised it was the right thing to do as he received an amazing outpour of love and support from the WWE Universe.
Reigns told the BBC: “It was a night of mixed emotions, you know.
“On one hand I was terrified, because I’m sharing this news with the whole world.
“A huge wave of opinions and criticism I knew was going to be coming my way.
“But on the other hand I was excited to finally be able to share this huge part of me, something I’ve kind of held a secret.
“To be honest, once I’d made the announcement, once I felt the crowd, and then on top of that, once the night was over, then I got the feedback through the social media, Twitter, Instagram, all the above, the outpour of love and support is what really made it known to me that this was the right thing to do.”
Reigns completed a miraculous recovery just four months later and returned to full-time action in WWE.
The former Universal Champion even had a big Singles Match at WrestleMania 35 as he beat Drew McIntyre.
The fans have also changed their attitude towards him as his story inspired them so much that they now cheer for him every time he performs.
The 34-year-old grappler is now set for a big fight against Shane McMahon at WWE Super ShowDown on June 7 at the King Abdullah International Stadium in Saudi Arabia.
Reigns also competed at Money in the Bank where he destroyed Elias in just 10 seconds.
He also looks set to face McMahon and McIntyre in a 2-on-1 Handicap Match at Extreme Rules on July 14 at the Wells Fargo Center in Philadelphia, Pennsylvania.