Choluria is the ‘earliest’ symptom of pancreatic cancer that strikes on the loo

The doctor said: “Bilirubin build-up (commonly known as jaundice) occurs when there are problems in the liver or a blockage in the bile duct.

“Blockage of the bile duct prevents the bile (containing bilirubin) from passing into the intestines and thus building up in the blood and urine. 

“This manifests as jaundice with darker yellow brown urine and yellowing of the skin and eyes. 

“The bile duct is located between the liver and the small intestine, next to the head of the pancreas.”